Synthesis and Characterization of Magnesium-Doped Brucinium Hydroxyapatite Nanoparticles for Biomedical Applications

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Swadhi R., Gayathri K., Anitha Rexalin D.

Abstract

In this examine, we document the synthesis and particular characterization of magnesium-doped Brucinium hydroxyapatite (Mg-Bruc-HAp) nanoparticles, targeting their capability packages within the biomedical area. Hydroxyapatite (HAp) is a bioactive ceramic acknowledged for its similarity to bone mineral, making it a top candidate for numerous biomedical programs, including bone regeneration and drug transport. To beautify its homes, we added magnesium ions into the Brucinium hydroxyapatite matrix, leveraging the acknowledged benefits of magnesium in bone metabolism and its potential to enhance the fabric’s bioactivity and stability


The Mg-Bruc-HAp nanoparticles have been synthesized the usage of a co-precipitation method, optimizing parameters together with pH, temperature, and response time to achieve uniform particle length and ideal morphology. The structural and compositional characteristics of the synthesized nanoparticles had been very well investigated the usage of X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), and electricity-dispersive X-ray spectroscopy (EDS). These analyses confirmed the a success incorporation of magnesium into the hydroxyapatite lattice and found out nanoscale debris with high surface place.

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