Retrospective Analysis of Adjuvant Propulsion Strategies in the Pharmacotherapy of Oral Lichen Planus (OLP)

Abstract

Oral lichen planus is a chronic inflammatory condition affecting the oral cavity. Various treatment modalities have been carried out in treating OLP out of which adjuvant antihistamine, antifungal therapies encores a crucial role. The core objective of the study was to assess the therapeutic effectiveness of the employed adjuvant Propulsion strategies,  by retrospectively extracting the data of patients who reported to the Department of Oral Medicine And Radiology And Special Care Dentistry using electronic data recording device of the institution from the time period of 2019-2023. Parameters such as patient’s age, gender, clinical variants of OLP,  underlying systemic disease, Conventional and adjuvant therapies employed and their respective VAS (Visual analogue scale)  and Lesion size (Thongprasom criteria)  were documented. The data were later statistically analyzed with SPSS Software version 26.0 by employing Fisher’s exact test, Chi square test and Independent samples Mann Whitney tests which  yielded a  significant P value of <0.001. Since oral lichen planus has a highest recurrence rate and slower cure, the use of adjuvant therapies along with the conventional therapies could be implicated, aiding in a synergistic action and faster resolution of the lesion