Analysing a Duo of Widespread Neurodegenerative Disorders: Exploring Their Roots, Clinical Expressions, Unfolding Processes, and the Arsenal of Available Therapies

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Dr V Sheeja Kumari, Dr G Vennira Selvi, Dr S Ponmaniraj, Dr R.Sivabalan, Mr. Devanolla Suresh, Asokkumar R

Abstract

This comprehensive analysis explores the complex factors contributing to neurodegenerative disorders, particularly Alzheimer's and Parkinson's diseases. It covers genetic and environmental influences, as well as the emerging field of epigenetics. The clinical aspects of these disorders, their diverse symptoms, and distinctions between them are examined. The analysis delves into cellular and molecular processes, focusing on pathological mechanisms and neuroinflammation driving disease progression. It also reviews current treatments, challenges in drug development, and promising emerging therapies like targeted therapies, gene therapies, and immunotherapies. Lifestyle interventions and disease prevention are emphasized for improving the quality of life for those at risk or already affected. The analysis stresses the urgency of ongoing research and development in this field, offering hope for unraveling the complexities of these conditions and developing more effective interventions.

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