A Review: Green Synthesis of Chalcone

Abstract

Chalcone is very promising drug molecule in modern day pharmaceutical field. This molecule has own various types of biological activity like anti-bacterial,anti-inflammatory,anti-amoebic,anticancer etc. If any electron withdrawing group like chloro,bromo, nitro etc. and any heteroaromatic ring insert into chalcone group or any heteroaromatic ring add by replace of any phenyl ring of chalcone then the potency and biological activity of chalcone will be enhanced. This is a review paper about finding suitable method for chalcone synthesis via green chemistry approaches.Recently green chemistry is emerging as a new goal of pharmaceutical industry. In this review, green chemistry methods are compared with conventional methods and ultimately which method is best this will be discussed. Conventionally method for synthesis of chalcone has many drawbacks,which are discussed later,green chemistry methods overcome this problem. In this article we have discussed about the conventional and all green synthetic methods of chalcone. Also discussed the all drawbacks of conventional methods and the advantages of green synthetic method over conventional method and determine the best green synthetic method for preparation of chalcone.