Microbiological Activities Of Para - Bromophenoxy Acetic Acid

Abstract

Para-bromophenoxyacetic acid's antimicrobial activity showed promise as it inhibited the growth of various microorganisms, including bacteria and fungi. The compound's bromo group appeared to have enhanced its effectiveness against these microorganisms, resulting in larger lethal zones compared to the standard drug, gentamicin. The antimicrobial assay demonstrated notable inhibitory effects on Bacillus subtilis, Enterobacter, E. coli, Klebsiella pneumoniae, Candida albicans, and Trichoderma. The potential modes of action involved the disruption of cell membranes, interference with cell wall synthesis, inhibition of protein or nucleic acid synthesis, or induction of reactive oxygen species. The compound's antimicrobial properties provided an intriguing avenue for future research into novel treatments against microbial infections.